Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361959 | 0.94 | LMNA (0.62) | HTTSMN1; SMN2ALDH1A1MAPTALOX15 | |
| SCHEMBL10361518 | 0.84 | LMNA (0.61) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL10362411 | 0.82 | LMNA (0.58) | HTTSMN1; SMN2ALDH1A1MAPTALOX15 | |
| SCHEMBL10361981 | 0.81 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1MAPTALOX15 | |
| SCHEMBL10362010 | 0.81 | LMNA (0.66) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL10362444 | 0.81 | LMNA (0.60) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL10767314 | 0.81 | LMNA (0.56) | HTTSMN1; SMN2ALDH1A1MAPTALOX15 | |
| SCHEMBL10361967 | 0.80 | HTT (0.53) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL10361963 | 0.79 | LMNA (0.70) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL10362381 | 0.79 | LMNA (0.56) | ALDH1A1LMNACACNA1GCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | claimed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | disclosed |