Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362072 | 0.83 | LMNA (0.54) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10361959 | 0.83 | LMNA (0.62) | LMNAKMT2AALDH1A1POLBCA1 | |
| SCHEMBL10363478 | 0.79 | HTT (0.57) | LMNAKMT2AALDH1A1POLBOPRD1 | |
| SCHEMBL10362411 | 0.76 | LMNA (0.58) | LMNAKMT2AALDH1A1POLB | |
| SCHEMBL11763515 | 0.75 | OPRD1 (0.55) | LMNAKMT2AALDH1A1POLBOPRD1 | |
| SCHEMBL9184019 | 0.75 | LMNA (0.47) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL10767314 | 0.74 | LMNA (0.56) | LMNAKMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9775427 | 0.74 | LMNA (0.60) | LMNACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL3631348 | 0.74 | LMNA (0.63) | LMNAALDH1A1OPRD1TDP1OPRM1 | |
| SCHEMBL17549667 | 0.74 | SLC6A4 (0.67) | LMNAKMT2AALDH1A1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | claimed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | claimed |
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | disclosed |