Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ADH5 | P11766 | 1/20 | 0.50 |
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | TGM1 | P22735 | 1/20 | 0.50 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236817 | 0.80 | KMT2A (0.68) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL7462893 | 0.78 | CYP3A4 (0.64) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL22661803 | 0.78 | CYP3A4 (0.64) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| Hydrochloric Acid SCHEMBL28418939 | 0.78 | KMT2A (0.67) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL29229571 | 0.77 | HTT (0.66) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL10808511 | 0.77 | FGFR1 (0.50) | TGM2LMNAF13A1TGM1TGM3 | |
| Acrylic Acid SCHEMBL28324903 | 0.76 | CYP3A4 (0.70) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL439369 | 0.76 | TGM2 (0.79) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL4912541 | 0.76 | KMT2A (0.61) | CYP3A4BAZ2BHTTENPP2MKNK1 | |
| SCHEMBL4661827 | 0.76 | CYP3A4 (0.53) | CYP3A4BAZ2BHTTENPP2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207901-B1 | ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4675319-A | Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use | RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1987-06-23 | — | — | US | disclosed |
| EP-0207901-A1 | Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1987-01-07 | — | — | EP | disclosed |