Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 2/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773308 | 0.72 | DAO (0.44) | DAOTDP2GRIN1GRIN2BMET | |
| SCHEMBL5012609 | 0.69 | NPC1 (0.41) | FBP1 | |
| SCHEMBL22319770 | 0.67 | KDM5B (0.35) | DAOTDP2GRIN1GRIN2BMET | |
| SCHEMBL11840289 | 0.65 | GRIN1 (0.36) | TDP2GRIN1GRIN2B | |
| SCHEMBL11033221 | 0.65 | ALDH1A1 (0.38) | — | |
| SCHEMBL21241348 | 0.65 | CYP2A6 (0.46) | — | |
| SCHEMBL2881603 | 0.65 | KDM5B (0.33) | TDP2GRIN1GRIN2B | |
| SCHEMBL28491322 | 0.63 | NOTUM (0.41) | TDP2 | |
| SCHEMBL30441982 | 0.63 | NOTUM (0.41) | TDP2 | |
| SCHEMBL18517201 | 0.63 | DAO (0.37) | DAOTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137534-B1 | ONE-POT PROCESS FOR PREPARATION OF 7BETA-AMINO- AND 7BETA-ACYLAMINO- 3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR DEOXYGENATION OF 7BETA-ACYLAMINO-3-CEPHEM-4-CARBOXYLIC ACID 1-OXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |