Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28491322 | 1.00 | NOTUM (0.41) | NOTUMTDP2DCTPP1RAB9ATSHR | |
| SCHEMBL6109363 | 0.84 | RAB9A (0.38) | NOTUMRAB9ATSHRHSD17B10GSK3B | |
| SCHEMBL3721048 | 0.78 | ALDH1A1 (0.47) | NOTUMRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL25488567 | 0.76 | ALDH1A1 (0.53) | DCTPP1RAB9ATSHRHSD17B10MEN1 | |
| SCHEMBL5273688 | 0.74 | TSHR (0.36) | RAB9ATSHRHSD17B10MEN1ALDH1A1 | |
| SCHEMBL5550526 | 0.72 | FEN1 (0.46) | — | |
| SCHEMBL29014019 | 0.72 | CYP1A2 (0.46) | DCTPP1RAB9ATSHRHSD17B10ALDH1A1 | |
| SCHEMBL11033221 | 0.72 | ALDH1A1 (0.38) | RAB9AHSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL10162230 | 0.71 | NPC1 (0.45) | NOTUMRAB9AMEN1KMT2AMAPT | |
| SCHEMBL12656532 | 0.71 | NOTUM (0.45) | NOTUMTDP2DCTPP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995620-B | Preparation method of 1,3, 4-thiadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |