Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731016 | 0.90 | TSHR (0.48) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL2412299 | 0.85 | IDO1 (0.44) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL2412297 | 0.85 | IDO1 (0.44) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL21863346 | 0.85 | MGLL (0.47) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL12172323 | 0.85 | MGLL (0.47) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL18876519 | 0.83 | TSHR (0.42) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL10362663 | 0.83 | TSHR (0.45) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL7236774 | 0.81 | IDO1 (0.44) | TSHRLMNAALDH1A1GLA | |
| SCHEMBL21715829 | 0.81 | SMN1; SMN2 (0.44) | TSHRLMNATDP1ALDH1A1TP53 | |
| SCHEMBL9234674 | 0.81 | AGXT (0.44) | TSHRLMNATDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150842-B1 | HALOGEN-SUBSTITUTED GLYCIDYL ETHER COMPOUND AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-27 | — | — | EP | disclosed |