Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364454 | 0.94 | PTGS2 (0.54) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL2116437 | 0.92 | PTGS2 (0.66) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17364452 | 0.91 | PTGS2 (0.51) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17364451 | 0.90 | SMN1; SMN2 (0.54) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17364453 | 0.88 | GAA (0.63) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17364456 | 0.88 | PTGS2 (0.49) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL2955123 | 0.87 | HPGD (0.50) | ALDH1A1CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL12061812 | 0.86 | GAA (0.66) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17365269 | 0.86 | PTGS2 (0.60) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL8879627 | 0.85 | POLB (0.53) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210849-B1 | 2-HYDROXY-3-PHENOXYPROPYL AMINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-4772631-A | Phenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-20 | — | — | US | disclosed |