Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17365271 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAHPGDGAANPSR1 | |
| SCHEMBL10364396 | 0.90 | PTGS2 (0.58) | SMN1; SMN2LMNAGAAPTGS2ALDH1A1 | |
| SCHEMBL17364454 | 0.85 | PTGS2 (0.54) | SMN1; SMN2LMNAGAAPTGS2ALDH1A1 | |
| SCHEMBL2116437 | 0.82 | PTGS2 (0.66) | SMN1; SMN2LMNAGAAPTGS2ALDH1A1 | |
| SCHEMBL17364452 | 0.82 | PTGS2 (0.51) | SMN1; SMN2LMNAGAAPTGS2ALDH1A1 | |
| SCHEMBL17364453 | 0.79 | GAA (0.63) | SMN1; SMN2LMNAGAANPSR1PTGS2 | |
| SCHEMBL17364456 | 0.79 | PTGS2 (0.49) | SMN1; SMN2LMNAPTGS2ALDH1A1CYP2C9 | |
| SCHEMBL2955123 | 0.78 | HPGD (0.50) | SMN1; SMN2HPGDGAAALDH1A1CYP2C9 | |
| SCHEMBL3401075 | 0.78 | MAOB (0.53) | SMN1; SMN2LMNAHPGDGAANPSR1 | |
| SCHEMBL13336515 | 0.77 | PTGS2 (0.50) | SMN1; SMN2LMNAHPGDGAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221949-B2 | Resin, optical material, and optical device | MITSUI CHEMICALS, INC. (JP) | 2015-12-29 | — | — | US | disclosed |