SCHEMBL10364401

SCHEMBL10364401

CC(COC(=O)C(C)(C)C)OCSCOC(=O)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6991459 0.81 PRKCA (0.42) PRKCA
SCHEMBL27646333 0.80 PRKCA (0.48) PRKCA
SCHEMBL27625810 0.78 PRKCA (0.47) PRKCA
SCHEMBL1640996 0.75 PRKCA (0.53) PRKCA
SCHEMBL538492 0.75 PRKCA (0.53) PRKCA
SCHEMBL1426847 0.75 PRKCA (0.44) PRKCA
SCHEMBL685935 0.75 PRKCA (0.55) PRKCA
SCHEMBL21501082 0.74 PRKCA (0.50) PRKCA
SCHEMBL17828577 0.74 PRKCA (0.50) PRKCA
SCHEMBL19636686 0.72 PRKCA (0.42) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152965-B1 PROCESS FOR PREPARING 2,6-SUBSTITUTED-9-(1,3-DIHYDROXY-2-PROPOXY-MENTHYL)-PURINES AND CERTAIN DERIVATIVES SYNTEX (U.S.A.) INC. (US) 1990-10-24 EP disclosed
US-4621140-A Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives SYNTEX (U.S.A.) INC. (US) 1986-11-04 US disclosed
EP-0152965-A2 Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxy-menthyl)-purines and certain derivatives SYNTEX (U.S.A.) INC. (US) 1985-08-28 EP disclosed