Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | BLM | P54132 | 4/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | THPO | P40225 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoetharine SCHEMBL29515330 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL3225540 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL56515 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL3218412 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL56516 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL21252711 | 0.87 | ADRB2 (1.00) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| Isoetharine SCHEMBL211343 | 0.86 | ADRB2 (0.97) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| SCHEMBL10363031 | 0.83 | ADRB2 (0.58) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| SCHEMBL28120299 | 0.83 | ADRB2 (0.58) | ADRB2PTGS2OPRK1SLC6A3KDM4E | |
| SCHEMBL19236267 | 0.83 | ADRB2 (0.71) | ADRB2PTGS2OPRK1SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185814-B1 | PHENYLSERINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |