Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866779 | 0.81 | NPC1 (0.54) | NPC1ALOX12KMT2AHPGDTSHR | |
| SCHEMBL11835354 | 0.81 | RAB9A (0.59) | NPC1KMT2AHPGDMAPK1TSHR | |
| SCHEMBL30578691 | 0.79 | NPC1 (0.55) | NPC1ALOX12KMT2AHPGDMAPK1 | |
| SCHEMBL2792565 | 0.74 | HPGD (0.51) | NPC1ALOX12KMT2AHPGDMAPK1 | |
| SCHEMBL10898999 | 0.74 | TDP1 (0.55) | NPC1HPGDMAPK1TSHRPOLB | |
| SCHEMBL13229668 | 0.73 | HRH3 (0.58) | NPC1ALOX12KMT2AHPGDMAPK1 | |
| SCHEMBL30578668 | 0.73 | POLB (0.64) | NPC1ALOX12KMT2AMAPK1POLB | |
| SCHEMBL13401661 | 0.71 | TAAR1 (0.36) | NPC1HPGDTSHRALDH1A1 | |
| SCHEMBL30578717 | 0.71 | POLB (0.63) | NPC1ALOX12KMT2AHPGDMAPK1 | |
| SCHEMBL29291081 | 0.71 | ALOX12 (0.51) | NPC1ALOX12KMT2AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008390-B | A kind of sulfenyl of oxadiazole containing 1,3,4- acetamide derivative, preparation method and applications | 贵州大学 | 2018-07-06 | — | — | CN | disclosed |
| EP-0228447-A4 | PESTICIDAL POLYHALOALKENE DERIVATIVES | — | 1990-12-27 | — | — | EP | disclosed |
| US-4952580-A | NEMATOCIDES, ANTHELMINTICS | FMC CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0228447-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC Corporation (US) | 1987-07-15 | — | — | EP | disclosed |
| WO-1986007590-A1 | PESTICIDAL POLYHALOALKENE DERIVATIVES | FMC CORPORATION (US) | 1986-12-31 | — | — | WO | disclosed |