Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799731 | 0.84 | CYP19A1 (0.48) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL10418945 | 0.83 | HSP90AA1 (0.48) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL6321049 | 0.80 | KMT2A (0.57) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL6202493 | 0.80 | MAPT (0.60) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL10469518 | 0.80 | CYP3A4 (0.44) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL10468609 | 0.78 | KMT2A (0.56) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL6222574 | 0.78 | CYP19A1 (0.49) | KMT2AMAPTCYP19A1CYP3A4MEN1 | |
| SCHEMBL9795408 | 0.77 | CYP19A1 (0.53) | KMT2AHTTLMNAMAPTCYP19A1 | |
| SCHEMBL10482566 | 0.77 | KMT2A (0.52) | KMT2AHTTLMNAMAPTHDAC1 | |
| SCHEMBL10879896 | 0.77 | CYP19A1 (0.49) | KMT2AHTTLMNAMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180838-B1 | SUBSTITUTED AZOLYLCYCLOPROPYL-AZOLYLMETHYL-CARBINOL-DERIVATIVES | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |
| US-4910213-A | Heterocyclic containing compound | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4875928-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0180835-B1 | ANTIMYCOTIC AZOLYLCYCLOPROPYLCARBINOL DERIVATIVES | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0180835-A2 | Antimycotic azolylcyclopropylcarbinol derivatives | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180838-A2 | Substituted azolylcyclopropyl-azolylmethyl-carbinol-derivatives | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |