Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11024517 | 0.82 | TAAR1 (0.52) | TAAR1MAOBESR2ALOX5PGR | |
| SCHEMBL30385 | 0.80 | CYP3A4 (0.60) | TAAR1MAOBALOX5 | |
| SCHEMBL30487714 | 0.80 | CYP3A4 (0.60) | TAAR1MAOBALOX5 | |
| SCHEMBL1623905 | 0.80 | TAAR1 (0.69) | TAAR1MAOBESR2ALOX5GRM2 | |
| SCHEMBL10363324 | 0.80 | GABRG2 (0.46) | MAOB | |
| SCHEMBL2614813 | 0.80 | IDO1 (0.57) | TAAR1 | |
| SCHEMBL1337544 | 0.80 | AGXT (0.43) | — | |
| SCHEMBL19523120 | 0.77 | MAOB (0.69) | TAAR1MAOBESR2ALOX5GRM2 | |
| SCHEMBL6968995 | 0.77 | AGXT (0.55) | TAAR1MAOBALOX5 | |
| SCHEMBL29997393 | 0.76 | TAAR1 (0.53) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210885-B1 | DERIVATIVES OF PRIMARY HALOBIPHENYL ALCOHOLS THERAPEUTICALLY USEFUL IN THE TREATMENT OF ARTERIOSCLEROSIS | PIERRE FABRE MEDICAMENT (FR) | 1990-07-11 | — | — | EP | claimed |
| US-4734417-A | Lipid- and cholesterol-reducing derivatives of halo-biphenyl primary alcohols | P.F. MEDICAMENT (FR) | 1988-03-29 | — | — | US | disclosed |