Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566142 | 0.87 | TNF (0.41) | TNFHPGDBRD4KMT2ASOS1 | |
| SCHEMBL10591648 | 0.84 | KMT2A (0.40) | TNFHPGDBRD4KMT2ASOS1 | |
| SCHEMBL16828803 | 0.79 | BRD4 (0.53) | TNFHPGDBRD4MAPTSOS1 | |
| SCHEMBL10581641 | 0.79 | BRD4 (0.51) | TNFHPGDBRD4SOS1KDM4E | |
| SCHEMBL23566144 | 0.76 | TNF (0.44) | TNFHPGDBRD4SOS1POLB | |
| SCHEMBL1045329 | 0.75 | TLR8 (0.49) | TNFHPGDBRD4MAPTKMT2A | |
| SCHEMBL10591397 | 0.73 | TNF (0.45) | TNFHPGDBRD4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10695240 | 0.73 | TLR8 (0.51) | TNFHPGDBRD4MAPTKMT2A | |
| SCHEMBL1417492 | 0.72 | ALDH1A1 (0.46) | TNFHPGDBRD4MAPTSOS1 | |
| SCHEMBL4734075 | 0.72 | BRD4 (0.57) | HPGDBRD4KMT2APOLBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314478-B1 | NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR PREPARATION THEREOF ANTIFUNGAL AGENT AND MILDEWPROOF AGENT | SHIKOKU CHEMICALS CORPORATION (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4912123-A | Imidazole compound | SHIKOKU CHEMICALS CORPORATION (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0314478-A1 | Novel imidazole compounds, process for preparation thereof antifungal agent and mildewproof agent | SHIKOKU CHEMICALS CORPORATION (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4720551-A | Chlorothienyl-imidazole propenones | SHIKOKU CHEMICALS CORPORATION (JP) | 1988-01-19 | — | — | US | disclosed |