Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416445 | 0.89 | CACNA1F (0.58) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7424363 | 0.83 | ADORA3 (0.58) | CACNA1BADORA3ADRA1ACACNA1FCACNA1D | |
| SCHEMBL10671428 | 0.81 | MEN1 (0.65) | ADORA3CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7034433 | 0.80 | CACNA1B (0.64) | CACNA1BADORA3ADRA1AADRA2AADRA2B | |
| SCHEMBL7433908 | 0.80 | CACNA1C (0.64) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7160127 | 0.79 | ADORA3 (0.78) | CACNA1BADORA3ADRA1AADRA2AADRA2B | |
| SCHEMBL7235504 | 0.78 | CACNA1B (0.59) | CACNA1BADORA3ADRA1AADRA2AADRA2B | |
| SCHEMBL10669458 | 0.76 | CACNA1C (0.59) | CACNA1BADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL10364949 | 0.76 | KMT2A (0.65) | CACNA1BADORA3MEN1ALDH1A1LMNA | |
| SCHEMBL9673699 | 0.76 | KDM4E (0.43) | TDP1MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126094-B1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL S.A. (CH) | 1990-06-20 | — | — | EP | disclosed |