Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 4/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365365 | 0.83 | ALDH1A1 (0.69) | SPRKDM4EALDH1A1MAPK11MAPK14 | |
| SCHEMBL10364566 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29419571 | 0.80 | MAPT (0.68) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL1335647 | 0.80 | MAPT (0.68) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10366047 | 0.80 | CNR1 (0.41) | POLBDRD2TYK2MEN1KMT2A | |
| SCHEMBL2854476 | 0.80 | MALT1 (0.56) | KDM4ESMN1; SMN2MALT1 | |
| SCHEMBL31684401 | 0.79 | MAPT (0.51) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL30147333 | 0.79 | MAPT (0.51) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2852540 | 0.79 | KDM4E (0.66) | SPRKDM4EALDH1A1MAPK11MAPK14 | |
| SCHEMBL2850157 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |