Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973462 | 1.00 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| Hydrochloric Acid SCHEMBL4797236 | 0.97 | DPP4 (0.48) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL21263995 | 0.75 | CHRNA7 (0.39) | LMNAALDH1A1 | |
| SCHEMBL26033140 | 0.75 | HTT (0.40) | LMNAHIF1AKDM4EALDH1A1 | |
| SCHEMBL28185990 | 0.75 | ADRB2 (0.50) | ADRA2ALMNAHIF1AKDM4E | |
| SCHEMBL23244675 | 0.75 | PYCR1 (0.40) | DPP4HTR2AALDH1A1 | |
| SCHEMBL28185987 | 0.75 | IDO1 (0.43) | LMNAALDH1A1 | |
| SCHEMBL1036920 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL1036918 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL10404165 | 0.74 | DPP4 (0.50) | DPP4F2HTR2ATAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627631-B1 | PYRROLIDINONES AS METAP2 INHIBITORS | MERCK PATENT GMBH (DE) | 2015-12-16 | — | — | EP | claimed |
| EP-0484437-A4 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | SEARLE & CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0484437-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. Searle & Co. (US) | 1992-05-13 | — | — | EP | claimed |
| US-4871748-A | RODENTICIDES | MAY & BAKER LIMITED (GB) | 1989-10-03 | — | — | US | claimed |
| EP-0041324-B1 | A NEW PHENYLPROPARGYLAMINE DERIVATIVE | MAY & BAKER LIMITED (GB) | 1983-06-08 | — | — | EP | claimed |
| US-4347252-A | Rodenticidal 1-(3,5-bistrifluoromethylphenyl)-3-(4-t-butylpiperidino)prop-1-yne | MAY & BAKER LTD. (GB) | 1982-08-31 | — | — | US | claimed |
| EP-0041324-A1 | A new phenylpropargylamine derivative | MAY & BAKER LIMITED (GB) | 1981-12-09 | — | — | EP | claimed |
| WO-2025051148-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技股份有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119320383-A | Nitrogen-containing heteroaryl compound, and preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024073106-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS INHIBITORS OF TAPS | TRACT PHARMACEUTICALS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| CN-112480112-B | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112480112-A | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-03-12 | — | — | CN | disclosed |
| US-9730976-B2 | Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers | BIONTECH AG (DE) | 2017-08-15 | — | — | US | disclosed |
| EP-0041324-B1 | A NEW PHENYLPROPARGYLAMINE DERIVATIVE | MAY & BAKER LIMITED (GB) | 1983-06-08 | — | — | EP | disclosed |
| EP-0041324-B1 | A NEW PHENYLPROPARGYLAMINE DERIVATIVE | MAY & BAKER LIMITED (GB) | 1983-06-08 | — | — | EP | disclosed |
| US-4347252-A | Rodenticidal 1-(3,5-bistrifluoromethylphenyl)-3-(4-t-butylpiperidino)prop-1-yne | MAY & BAKER LTD. (GB) | 1982-08-31 | — | — | US | disclosed |
| US-4347252-A | Rodenticidal 1-(3,5-bistrifluoromethylphenyl)-3-(4-t-butylpiperidino)prop-1-yne | MAY & BAKER LTD. (GB) | 1982-08-31 | — | — | US | disclosed |
| EP-0041324-A1 | A new phenylpropargylamine derivative | MAY & BAKER LIMITED (GB) | 1981-12-09 | — | — | EP | disclosed |
| EP-0041324-A1 | A new phenylpropargylamine derivative | MAY & BAKER LIMITED (GB) | 1981-12-09 | — | — | EP | disclosed |
| EP-0041324-A1 | A new phenylpropargylamine derivative | MAY & BAKER LIMITED (GB) | 1981-12-09 | — | — | EP | disclosed |