Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 13/20 | 0.72 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.72 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.72 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.72 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.72 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.72 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.63 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | GABRE | P78334 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334382 | 0.92 | GABRA1 (0.75) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Iomazenil (123I) SCHEMBL29374678 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Iomazenil SCHEMBL41658 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9745968 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Iomazenil (123I) SCHEMBL17022271 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Iomazenil SCHEMBL29385986 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Sarmazenil SCHEMBL195304 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7329697 | 0.89 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10627713 | 0.88 | GABRA1 (0.70) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11887388 | 0.87 | GABRA1 (0.68) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241682-B1 | NOVEL BENZODIAZEPINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |
| US-4772599-A | ANTICONVULSANTS, ANXIOLYTICS, HYPNOTICS, NOOTROPICS | A/S FERROSAN (DK) | 1988-09-20 | — | — | US | disclosed |
| EP-0241682-A2 | Novel benzodiazepine derivatives and their preparation and use | NOVO NORDISK A/S (DK) | 1987-10-21 | — | — | EP | disclosed |