Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110740 | 0.87 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2AMAPTMITF | |
| SCHEMBL11105233 | 0.85 | POLB (0.47) | SMN1; SMN2MEN1KMT2AMAPTMITF | |
| SCHEMBL10365806 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL10365714 | 0.80 | MAPK1 (0.38) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9489658 | 0.78 | RXFP1 (0.51) | SMN1; SMN2MEN1KMT2AMAPTMITF | |
| SCHEMBL8192778 | 0.77 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11102330 | 0.77 | APOBEC3A (0.53) | MAPTALDH1A1RXFP1KDM4EPOLB | |
| SCHEMBL11104339 | 0.75 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1RXFP1KDM4E | |
| SCHEMBL7802413 | 0.75 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10365355 | 0.75 | GRM7 (0.39) | KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218972-B1 | BENZOTHIAZOLONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-07 | — | — | EP | disclosed |
| US-4888428-A | HERBICIDE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-12-19 | — | — | US | disclosed |
| US-4720297-A | Benzothiazolones, and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0218972-A1 | Benzothiazolones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-22 | — | — | EP | disclosed |