Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110740 | 0.79 | MEN1 (0.42) | RXFP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10366017 | 0.78 | SMN1; SMN2 (0.41) | RXFP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11105233 | 0.77 | POLB (0.47) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL9735326 | 0.74 | PLK1 (0.44) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL11102992 | 0.68 | POLB (0.49) | RXFP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9741534 | 0.68 | POLB (0.38) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL11102330 | 0.68 | APOBEC3A (0.53) | RXFP1ALDH1A1NPSR1MAPTGSK3A | |
| SCHEMBL4616232 | 0.67 | TDP1 (0.67) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL7231594 | 0.67 | ALDH1A1 (0.46) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL7802413 | 0.67 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2290863-A | — | — | None | — | — | JP | disclosed |
| US-5183898-A | Chemical intermediate for fungicide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |
| US-5093345-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| JP-H02290863-A | NITRO-SUBSTITUTED BENZOTHIAZOLONE, THEIR PRODUCTION AND THEIR USE AS HARMFUL ORGANISM CONTROL AGENT AND NOVEL INTERMEDIATE | BAYER AG | 1990-11-30 | — | — | JP | disclosed |
| EP-0391186-A1 | Nitro substituted benzotiazolones, process for their production and their use as pesticides and new intermediates | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |