Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 7/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367046 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10364516 | 0.87 | CCR1 (0.51) | KDM4EALDH1A1POLBSMN1; SMN2CCR1 | |
| SCHEMBL10365138 | 0.87 | CCR1 (0.56) | MAPTCCR1 | |
| SCHEMBL10367084 | 0.86 | ALDH1A1 (0.76) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10365382 | 0.85 | CCR1 (0.49) | POLBCCR1KMT2A | |
| SCHEMBL2296037 | 0.85 | POLB (0.74) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10367005 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10365693 | 0.84 | ELANE (0.51) | KDM4EALDH1A1POLBSMN1; SMN2CCR1 | |
| SCHEMBL2859642 | 0.82 | CCR1 (0.73) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854432 | 0.82 | CCR1 (0.68) | CCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |