Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026287 | 0.84 | SMN1; SMN2 (0.39) | KDM4EMAPTTSHR | |
| SCHEMBL4409393 | 0.83 | — | — | |
| SCHEMBL5698996 | 0.79 | — | — | |
| SCHEMBL15546835 | 0.79 | — | — | |
| SCHEMBL20173417 | 0.79 | MLKL (0.41) | KDM4EGAAMAPTTSHR | |
| SCHEMBL5894634 | 0.77 | TSHR (0.44) | MAPTTSHR | |
| SCHEMBL1345605 | 0.77 | DAO (0.35) | DAOHDAC8HDAC6NAPRTKDM4E | |
| SCHEMBL10538853 | 0.76 | CA1 (0.42) | KDM4ETSHR | |
| SCHEMBL19190945 | 0.75 | — | — | |
| SCHEMBL5756561 | 0.75 | KDM5A (0.33) | DAOHDAC8HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180838-B1 | SUBSTITUTED AZOLYLCYCLOPROPYL-AZOLYLMETHYL-CARBINOL-DERIVATIVES | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |