⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756561 | 0.81 | KDM5A (0.33) | — | |
| SCHEMBL10366551 | 0.79 | DAO (0.37) | — | |
| SCHEMBL75926 | 0.79 | — | — | |
| SCHEMBL456256 | 0.79 | DAO (0.32) | — | |
| SCHEMBL4409393 | 0.79 | — | — | |
| SCHEMBL23079299 | 0.75 | — | — | |
| SCHEMBL4700498 | 0.75 | — | — | |
| SCHEMBL4581201 | 0.75 | — | — | |
| SCHEMBL25423722 | 0.75 | — | — | |
| SCHEMBL13754484 | 0.75 | DAO (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664027-A1 | SUBSTITUTED 2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1519921-A2 | SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE | Amgen Inc. (US) | 2005-04-06 | — | — | EP | claimed |
| WO-2005021532-A1 | SUBSTITUTED 2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND METHODS OF USE | AMGEN INC (US) | 2005-03-10 | — | — | WO | claimed |
| WO-2004005279-A2 | SUBSTITUTED ANTHRANILIC AMIDE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2004-01-15 | — | — | WO | claimed |
| EP-1358184-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | Amgen Inc. (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002066470-A1 | SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2002-08-29 | — | — | WO | claimed |
| US-4911746-A | Containing a phenyl ring and an imidazole or a 1,2,4-triazole ring | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| US-4904298-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | claimed |
| US-4897107-A | PLANT GROWTH REGULATORS; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| US-4871390-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | claimed |
| US-4870093-A | MEDICINAL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | claimed |
| US-4789672-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | claimed |
| CN-87104499-A | Novel alginic acid esters | — | 1988-04-06 | — | — | CN | claimed |
| US-4652579-A | AZOLE FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | claimed |
| EP-0072580-B1 | 1-HYDROXYETHYL-AZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS AND FUNGICIDES | BAYER AG (DE) | 1987-02-25 | — | — | EP | claimed |
| EP-0087148-B1 | 1-HYDROXYETHYL-AZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS AND FUNGICIDES | BAYER AG (DE) | 1986-03-19 | — | — | EP | claimed |
| EP-0040345-B1 | 1-HYDROXYETHYL-AZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE REGULATION OF PLANT GROWTH AND AS FUNGICIDES | BAYER AG (DE) | 1984-07-11 | — | — | EP | claimed |
| EP-0043419-B1 | ANTIMYCOTIC COMPOSITION | BAYER AG (DE) | 1984-03-14 | — | — | EP | claimed |
| JP-2167273-A | — | — | None | — | — | JP | disclosed |
| EP-0040345-A1 | 1-Hydroxyethyl-azole derivatives, process for their preparation and their use in the regulation of plant growth and as fungicides | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |