Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660494 | 0.89 | KDM4E (0.34) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10367572 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL7287680 | 0.86 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10366385 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10366230 | 0.84 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10373828 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10368645 | 0.83 | GAA (0.41) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10366069 | 0.82 | MAPT (0.43) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL7290530 | 0.81 | PDE4A (0.38) | KDM4EALDH1A1MAPTGAARECQL | |
| SCHEMBL10665164 | 0.81 | MEN1 (0.46) | KDM4EALDH1A1MAPTGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190367-B1 | BENZO ADH BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-17 | — | — | EP | disclosed |
| US-4782057-A | ANTIDOTES FOR OVERSEDATION, ANXIOLYTICS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0190367-A1 | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |