Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373269 | 0.90 | PTGS2 (0.40) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9601954 | 0.89 | MAOB (0.40) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10365659 | 0.89 | GRM5 (0.38) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9601936 | 0.88 | MAOB (0.40) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10367572 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7287680 | 0.86 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10366559 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10368645 | 0.85 | GAA (0.41) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10367909 | 0.85 | GRM5 (0.36) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9602162 | 0.84 | MAOB (0.37) | KDM4EALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190367-B1 | BENZO ADH BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-17 | — | — | EP | disclosed |
| US-4782057-A | ANTIDOTES FOR OVERSEDATION, ANXIOLYTICS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0190367-A1 | BENZO ADh BDCINNOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MECIDINAL COMPOSITION CONTAINING THEM | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |