Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269849 | 0.88 | ALDH1A1 (0.66) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10366875 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10366874 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10568256 | 0.87 | MAPT (0.54) | ALDH1A1CYP3A4KMT2AHSP90AA1RAB9A | |
| SCHEMBL11028059 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10638069 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10408719 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10631729 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10422763 | 0.84 | CYP3A4 (0.55) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 | |
| SCHEMBL10628754 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP3A4KMT2ATSHRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141204-B1 | HYDROXYETHYL AZOLE DERIVATIVES | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| US-4843088-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |
| US-4645767-A | FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-24 | — | — | US | disclosed |
| EP-0141204-A2 | Hydroxyethyl azole derivatives | BAYER AG (DE) | 1985-05-15 | — | — | EP | disclosed |