Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408611 | 0.90 | MAPT (0.53) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10545905 | 0.89 | MAPT (0.58) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10366604 | 0.87 | ALDH1A1 (0.55) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10628712 | 0.84 | MAPT (0.53) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10515326 | 0.82 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10361043 | 0.81 | HSP90AA1 (0.52) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10851596 | 0.81 | MAPT (0.60) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10830390 | 0.81 | MAPT (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10808470 | 0.78 | MAPT (0.56) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4097760 | 0.78 | MAPT (0.52) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843088-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | claimed |