Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683704 | 0.84 | PPARG (0.56) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| SCHEMBL6903859 | 0.83 | PPARG (0.52) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| SCHEMBL10686431 | 0.81 | PPARG (0.52) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| SCHEMBL10690190 | 0.81 | PPARG (0.52) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| SCHEMBL10686465 | 0.79 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| Englitazone SCHEMBL29377687 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| Englitazone SCHEMBL4727851 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| Englitazone SCHEMBL20125577 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| Englitazone SCHEMBL20125579 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 | |
| Englitazone SCHEMBL37697 | 0.77 | PPARG (0.50) | PPARGFFAR1MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207605-B1 | HYPOGLYCEMIC THIAZOLIDINEDIONES | PFIZER INC. (US) | 1990-02-07 | — | — | EP | claimed |
| US-20070249561-A1 | Pharmacological method for treatment of neuropathic pain | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | 2007-10-25 | — | — | US | disclosed |
| US-20070249561-A1 | Pharmacological method for treatment of neuropathic pain | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249561-A1 | Pharmacological method for treatment of neuropathic pain | PPARG, PPARA, CNR2 | PPARG 1/4885FFAR1 167/4885MAPT 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.