⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL29617701 | 1.00 | — | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL3809748 | 0.98 | PNMT (0.35) | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL30582725 | 0.98 | PNMT (0.35) | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL27709534 | 0.98 | PNMT (0.35) | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL4573663 | 0.98 | PNMT (0.35) | — | |
| 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine SCHEMBL2704396 | 0.89 | DRD2 (0.37) | — | |
| SCHEMBL588622 | 0.81 | PNMT (0.52) | — | |
| SCHEMBL12822 | 0.81 | PNMT (0.52) | — | |
| SCHEMBL30331914 | 0.81 | PNMT (0.52) | — | |
| Hydrochloric Acid SCHEMBL2378664 | 0.79 | PNMT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109702-A1 | NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF | GENOSCO INC (US) | 2026-04-23 | — | — | US | claimed |
| WO-2024211346-A1 | MUTANT PI3K-ALPHA INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-10-10 | — | — | WO | claimed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | claimed |
| US-11434247-B1 | Substituted furanopyrimidine compounds as PDE1 inhibitors | DART NEUROSCIENCE LLC (US) | 2022-09-06 | — | — | US | claimed |
| EP-3717488-B1 | SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORS | DART NEUROSCIENCE LLC (US) | 2021-09-29 | — | — | EP | claimed |
| US-20210244717-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2021-08-12 | — | — | US | claimed |
| EP-3717488-A1 | SUBSTITUTED FURANOPYRIMIDINE COMPOUNDS AS PDE1 INHIBITORS | Dart NeuroScience, LLC (US) | 2020-10-07 | — | — | EP | claimed |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| CN-111655695-A | Substituted furopyrimidines as PDE1 inhibitors | 达特神经科学有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-107827816-B | Method for synthesizing formamide derivative through graphene oxide catalytic formylation reaction | 湘潭大学 | 2020-01-10 | — | — | CN | claimed |
| EP-2280964-A1 | CHLOROTHIOPHENE-ISOXAZOLES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | Sanofi-Aventis (FR) | 2011-02-09 | — | — | EP | claimed |
| EP-2254881-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | Sanofi-Aventis (FR) | 2010-12-01 | — | — | EP | claimed |
| CN-101835755-A | Novel kinase inhibitors | HOFFMANN LA ROCHE | 2010-09-15 | — | — | CN | claimed |
| EP-2205564-A1 | NOVEL KINASE INHIBITORS | F. Hoffmann-Roche AG (CH) | 2010-07-14 | — | — | EP | claimed |
| WO-2009103440-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | claimed |
| WO-2009103439-A1 | CHLOROTHIOPHENE-ISOXAZOLES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | claimed |
| WO-2009053269-A1 | NOVEL KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | claimed |
| US-20090105209-A1 | BTK protein kinase inhibitors | ROCHE PALO ALTO LLC | 2009-04-23 | — | — | US | claimed |
| US-5312823-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | claimed |
| EP-0520277-A2 | 7-Azaisoindolinyl-quinolone- and naphthyridoncarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | claimed |