Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803116 | 0.81 | MEN1 (0.40) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL24427304 | 0.74 | MEN1 (0.48) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL24427705 | 0.71 | MEN1 (0.38) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL24427305 | 0.71 | MEN1 (0.38) | MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL7448295 | 0.69 | ALDH1A1 (0.42) | MEN1ALDH1A1GAAKMT2AHTR2A | |
| SCHEMBL1575886 | 0.68 | NOTUM (0.66) | HTR2AHTR2CHTR2BNOTUMTNF | |
| SCHEMBL9867062 | 0.68 | PGR (0.30) | — | |
| SCHEMBL10433910 | 0.68 | PGR (0.30) | — | |
| SCHEMBL25430744 | 0.64 | EGFR (0.45) | ALDH1A1GAAHTR2AHTR2CHTR2B | |
| SCHEMBL31552720 | 0.64 | KMT2A (0.55) | MEN1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165375-B1 | DERIVATIVE OF PYRIDO-BENZOTHIAZINE WITH HIGH ANTI-MICROBIAL ACTIVITY | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1990-10-17 | — | — | EP | claimed |
| US-4668784-A | HALOANILINE WITH POTASSIUM THIOCYANATE | MEDIOLANUM FARMACEUTICI S.R.L. (IT) | 1987-05-26 | — | — | US | claimed |
| US-4910196-A | Highly soluble antibacterially active organic salts of pyridobenzothiazines | MEDIOLANUM FARMACEUTICI SRL (IT) | 1990-03-20 | — | — | US | disclosed |
| EP-0252352-A2 | Highly soluble antibacterially active organic salts of pyridobenzothiazines and their preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1988-01-13 | — | — | EP | disclosed |