SCHEMBL10367256

SCHEMBL10367256

O=S(=O)(N(CC1CO1)CC1CO1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.40
MMP1 P03956 6/20 0.35
MMP2 P08253 6/20 0.35
MMP9 P14780 6/20 0.35
MMP8 P22894 6/20 0.35
MMP13 P45452 6/20 0.35
CA1 P00915 3/20 0.35
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10368279 1.00 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL11345149 0.91 CA2 (0.36) CA2MMP1MMP2MMP9MMP8
SCHEMBL1633836 0.88 CA2 (0.34) CA2MMP1MMP2MMP9MMP8
SCHEMBL7144799 0.84 CA2 (0.38) CA2MMP1MMP2MMP9MMP8
SCHEMBL10368080 0.84 CA2 (0.31) CA2MMP1MMP2MMP9MMP8
SCHEMBL1068424 0.82 CA2 (0.35) CA2MMP1MMP2MMP9MMP8
SCHEMBL10367192 0.78 TSHR (0.38) CA2MMP1MMP2MMP9MMP8
SCHEMBL10368095 0.76 MEN1 (0.33) CA2
SCHEMBL29910639 0.71 CA2 (0.43) CA2MMP1MMP2MMP9MMP8
SCHEMBL890734 0.71 CA2 (0.46) CA2MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125826-B1 FLUOROALIPHATIC SULFONAMIDES CONTAINING OXIRANE GROUPS AND/OR N-B-HYDROXYALKYLENE GROUPS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-14 EP claimed
US-4533713-A WATERPROOFING, OIL-REPELLANT CURED POLYEPOXIDES; PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US claimed
EP-0125826-A2 Fluoroaliphatic sulfonamides containing oxirane groups and/or N-B-hydroxyalkylene groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-11-21 EP claimed
EP-0125826-B1 FLUOROALIPHATIC SULFONAMIDES CONTAINING OXIRANE GROUPS AND/OR N-B-HYDROXYALKYLENE GROUPS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-14 EP disclosed
US-4533713-A WATERPROOFING, OIL-REPELLANT CURED POLYEPOXIDES; PROTECTIVE COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0125826-A2 Fluoroaliphatic sulfonamides containing oxirane groups and/or N-B-hydroxyalkylene groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-11-21 EP disclosed