Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367256 | 0.78 | CA2 (0.40) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10368279 | 0.78 | CA2 (0.40) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10367820 | 0.76 | CA2 (0.40) | TSHRSMN1; SMN2CA2ALDH1A1TDP1 | |
| SCHEMBL5152620 | 0.76 | CA1 (0.34) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL17956606 | 0.75 | F2 (0.37) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5551714 | 0.74 | CA2 (0.35) | TSHRCA2MAPK1CA1MMP1 | |
| SCHEMBL1633836 | 0.74 | CA2 (0.34) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL441682 | 0.74 | CA2 (0.35) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL15932430 | 0.74 | MMP1 (0.36) | TSHRCA2MAPK1CA1MMP1 | |
| SCHEMBL11345149 | 0.73 | CA2 (0.36) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125826-B1 | FLUOROALIPHATIC SULFONAMIDES CONTAINING OXIRANE GROUPS AND/OR N-B-HYDROXYALKYLENE GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-11-14 | — | — | EP | claimed |
| US-4533713-A | WATERPROOFING, OIL-REPELLANT CURED POLYEPOXIDES; PROTECTIVE COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-08-06 | — | — | US | claimed |
| EP-0125826-A2 | Fluoroaliphatic sulfonamides containing oxirane groups and/or N-B-hydroxyalkylene groups | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-11-21 | — | — | EP | claimed |
| EP-0125826-B1 | FLUOROALIPHATIC SULFONAMIDES CONTAINING OXIRANE GROUPS AND/OR N-B-HYDROXYALKYLENE GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4533713-A | WATERPROOFING, OIL-REPELLANT CURED POLYEPOXIDES; PROTECTIVE COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0125826-A2 | Fluoroaliphatic sulfonamides containing oxirane groups and/or N-B-hydroxyalkylene groups | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |