Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365699 | 0.84 | CDC7 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL10365452 | 0.83 | CYP3A4 (0.38) | MAPTMEN1LMNAKMT2AXIAP | |
| SCHEMBL1260040 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL17212174 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL1260873 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL31479971 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL27604844 | 0.75 | PIK3CD (0.46) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10364884 | 0.74 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL10365456 | 0.74 | HTR2C (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL10365587 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199968-B1 | THIAZOLE DERIVATIVES | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4804668-A | CARDIOTONIC AGENTS | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0199968-A1 | Thiazole derivatives | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-11-05 | — | — | EP | disclosed |