SCHEMBL31479971

SCHEMBL31479971

COC(=O)c1nc(-c2ccnnc2)cs1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
MPL P40238 1/20 0.40
HPGDS O60760 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 4/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
MCL1 Q07820 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HSD17B10 Q99714 2/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2176868 0.81 RAB9A (0.53) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL31479956 0.81 HCAR2 (0.44) ALDH1A1NPC1RAB9AMPLMEN1
SCHEMBL14368139 0.79 MEN1 (0.40) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL17212174 0.77 ALDH1A1 (0.42) ALDH1A1HPGDSGABRG2GABRB3GABRA5
SCHEMBL14368137 0.76 CYP3A4 (0.52) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL10367261 0.75 KDM4E (0.42) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL12571467 0.75 MAOA (0.53) ALDH1A1NPC1RAB9AHPGDSHPGD
SCHEMBL22352575 0.74 TSHR (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL31479959 0.73 SCN10A (0.41) ALDH1A1HPGDSMAPK1CYP19A1STING1
SCHEMBL1682685 0.72 MEN1 (0.41) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082460-A1 DIACYLGLYCEROL KINASE INHIBITOR COMPOUND AND USE THEREOF 上海先祥医药科技有限公司 2025-04-24 WO disclosed