Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367401 | 1.00 | MAOB (0.68) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL1524697 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155055 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155054 | 0.83 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL4392839 | 0.81 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL10366617 | 0.81 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL18595441 | 0.79 | MAOB (0.71) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL433496 | 0.79 | MAOB (0.71) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL28679572 | 0.79 | MAOB (0.71) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL10367681 | 0.78 | SIGMAR1 (0.43) | MAOBIDO1MAPK1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164075-B1 | 7-OXABICYCLOHEPTANE SUBSTITUTED THIO PROSTAGLANDIN ANALOGS | E.R. Squibb & Sons, Inc. (US) | 1990-09-12 | — | — | EP | disclosed |