Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | GPR52 | Q9Y2T5 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679572 | 1.00 | MAOB (0.71) | MAOBTOP1GPR52CA1CA2 | |
| SCHEMBL433496 | 1.00 | MAOB (0.71) | MAOBTOP1GPR52CA1CA2 | |
| SCHEMBL9715286 | 0.90 | GPR52 (0.57) | MAOBGPR52ALDH1A1HPGDALOX15 | |
| SCHEMBL7762164 | 0.90 | GPR52 (0.57) | MAOBGPR52ALDH1A1HPGDALOX15 | |
| SCHEMBL7762166 | 0.90 | GPR52 (0.57) | MAOBGPR52ALDH1A1HPGDALOX15 | |
| SCHEMBL9872529 | 0.88 | MAOB (0.56) | MAOBTOP1GPR52CA1CA2 | |
| SCHEMBL9872528 | 0.88 | MAOB (0.56) | MAOBTOP1GPR52CA1CA2 | |
| SCHEMBL28645454 | 0.85 | MAOB (0.62) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL1524697 | 0.84 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155054 | 0.84 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586981-B2 | Z-selective metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-03-07 | — | — | US | disclosed |