Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154468 | 1.00 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL10370403 | 1.00 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL29966226 | 1.00 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL6310987 | 0.98 | PRMT6 (0.62) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL27650580 | 0.94 | PRMT6 (0.58) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL11339852 | 0.86 | PRMT6 (0.78) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL11192726 | 0.86 | PRMT6 (0.78) | ALDH1A1SMN1; SMN2TDP1CYP2D6CYP2C9 | |
| SCHEMBL7955357 | 0.82 | HRH3 (0.63) | DRD2HRH3 | |
| SCHEMBL24556358 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TDP1KDM4EDRD2 | |
| SCHEMBL10370696 | 0.82 | MC4R (0.62) | ALDH1A1PRMT6KDM4EDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150073-B1 | 3,4-DISUBSTITUTED-1,2,5-OXADIAZOLES HAVING HISTAMINE H2-RECEPTOR ANTAGONIST ACTIVITY | Bristol-Myers Squibb Company (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0150073-A1 | 3,4-Disubstituted-1,2,5-oxadiazoles having histamine H2-receptor antagonist activity | Bristol-Myers Squibb Company (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4507485-A | 3,4-Disubstituted-1,2,5-oxadiazoles having histamine H2 -receptor antagonist activity | BRISTOL-MYERS COMPANY (US) | 1985-03-26 | — | — | US | disclosed |