Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994652 | 0.84 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL9359928 | 0.79 | LMNA (0.32) | KMT2AMEN1LMNA | |
| SCHEMBL2992989 | 0.78 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL19267936 | 0.78 | POLB (0.41) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL270080 | 0.77 | TSHR (0.56) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL816663 | 0.76 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL11811797 | 0.75 | TSHR (0.60) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL15001241 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL11490274 | 0.74 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL2984744 | 0.74 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832596-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT FINANCE BVI LTD (VG) | 2011-01-26 | — | — | EP | claimed |
| US-20070210288-A1 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | CLARIANT INTERNATIONAL LTD | 2007-09-13 | — | — | US | claimed |
| EP-1832596-A1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-12 | — | — | EP | claimed |
| EP-1832596-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT FINANCE BVI LTD (VG) | 2011-01-26 | — | — | EP | disclosed |
| US-7485745-B2 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-03 | — | — | US | disclosed |
| US-20070210288-A1 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | CLARIANT INTERNATIONAL LTD | 2007-09-13 | — | — | US | disclosed |
| EP-1832596-A1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-12 | — | — | EP | disclosed |
| US-5334760-A | Reacting a dichlorophosphine compound with acrylic acid or methacrylic acid in presence of a peroxide or an azo catalysts then hydration | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070210288-A1 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | ALKBH3, FFAR3, EBP | TSHR 1202/4885KMT2A 1684/4885MEN1 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.