Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366891 | 0.83 | SMN1; SMN2 (0.51) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10368396 | 0.80 | CNR1 (0.39) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10366228 | 0.80 | BPTF (0.40) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9726895 | 0.70 | PDE9A (0.45) | SMN1; SMN2KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9777009 | 0.70 | TDP1 (0.49) | SMN1; SMN2KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10602679 | 0.69 | NR3C1 (0.44) | CNR2SMN1; SMN2KMT2ARAB9AALDH1A1 | |
| SCHEMBL10365661 | 0.67 | BPTF (0.52) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10368922 | 0.66 | SMN1; SMN2 (0.36) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10366655 | 0.66 | SMN1; SMN2 (0.50) | CNR1CNR2SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10367935 | 0.65 | BRD9 (0.38) | CNR2SMN1; SMN2KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |