Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261062 | 0.87 | PARP1 (0.54) | PARP1SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL6556019 | 0.83 | PARP1 (0.50) | PARP1SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL15514834 | 0.75 | SLC9A1 (0.48) | PARP1MEN1KMT2AMTNR1A | |
| SCHEMBL5785526 | 0.75 | PARP1 (0.47) | PARP1SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL11776414 | 0.75 | MGAM (0.42) | MEN1KMT2ALMNAKDM4EMTNR1A | |
| SCHEMBL31500578 | 0.75 | PARP1 (0.47) | PARP1SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL29177217 | 0.74 | PARP1 (0.60) | PARP1SLC6A4 | |
| SCHEMBL29177346 | 0.74 | PARP1 (0.42) | PARP1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL29177184 | 0.74 | PARP1 (0.42) | PARP1 | |
| SCHEMBL1502069 | 0.74 | PARP1 (1.00) | PARP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-0301371-B1 | BENZOFURAN CARBOXAMIDES WITH BASIC SUBSTITUENTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1990-12-12 | — | — | EP | disclosed |
| US-4122204-A | MITICIDES, INSECTICIDES | UNION CARBIDE CORPORATION (US) | 1978-10-24 | — | — | US | disclosed |
| US-4013774-A | INSECTICIDAL N-THIO-SUBSTITUTED CARBAMATES OF DIHYDROBENZOFURANOLS | CHEVRON RESEARCH COMPANY (US) | 1977-03-22 | — | — | US | disclosed |