Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870918 | 0.81 | ACE (0.42) | ACE | |
| SCHEMBL10369668 | 0.76 | ACE (0.42) | ACE | |
| SCHEMBL10369717 | 0.76 | ACE (0.47) | ACE | |
| SCHEMBL10870638 | 0.75 | ACE (0.41) | ACE | |
| SCHEMBL10367995 | 0.73 | ACE (0.60) | ACE | |
| SCHEMBL10372193 | 0.71 | ACE (0.44) | ACE | |
| SCHEMBL10368378 | 0.68 | ACE (0.53) | ACE | |
| SCHEMBL10369195 | 0.65 | ALDH1A1 (0.37) | ACE | |
| SCHEMBL10368375 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL9789687 | 0.62 | ACE (0.61) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184861-B1 | DERIVATIVES OF THE 3-MERCAPTO-2-OXO-1-PYRROLIDINACETIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PROTER S.p.A. (IT) | 1990-06-06 | — | — | EP | disclosed |