Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479140 | 0.93 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1RAB9ANPC1CASP1 | |
| SCHEMBL9806734 | 0.85 | CYSLTR1 (0.74) | CYSLTR2CYSLTR1ALDH1A1GAAKMT2A | |
| SCHEMBL9479611 | 0.84 | EPHX2 (0.57) | RAB9ANPC1CASP1HPGDALDH1A1 | |
| SCHEMBL9806759 | 0.84 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1ALDH1A1KDM4EMAPT | |
| SCHEMBL9480363 | 0.82 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1RAB9ANPC1CASP1 | |
| SCHEMBL8998287 | 0.82 | CYSLTR2 (0.74) | CYSLTR2CYSLTR1MAPTMEN1KMT2A | |
| SCHEMBL8951280 | 0.81 | RAB9A (0.52) | RAB9ANPC1CASP1HPGDALDH1A1 | |
| SCHEMBL9479319 | 0.79 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9479142 | 0.79 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1LMNA | |
| SCHEMBL9479187 | 0.79 | RAB9A (0.51) | RAB9ANPC1CASP1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | disclosed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | disclosed |