SCHEMBL10370233

SCHEMBL10370233

CN1CCCCC1NC(=N)N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.33
CYP1A2 P05177 1/20 0.32
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8571021 0.82 HTT (0.36)
SCHEMBL10520187 0.76 HTT (0.37)
SCHEMBL6017513 0.74
SCHEMBL9394736 0.72 CYP1A2 (0.39) CYP1A2
SCHEMBL9037205 0.72 L3MBTL1 (0.46)
SCHEMBL723049 0.72
SCHEMBL14076271 0.69 CA1 (0.40)
SCHEMBL23060611 0.67
SCHEMBL9054844 0.67
SCHEMBL9612621 0.67 NCF1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157762-B1 NEW SUBSTITUTED PIPERIDINOGUANIDINES, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOUCHARA S.A. (FR) 1990-08-08 EP claimed
EP-0105881-A1 NEW CYANOGUANIDINES, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. BOUCHARA EMILE (FR) 1984-04-25 EP disclosed
WO-1983003607-A1 NEW CYANOGUANIDINES, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CORNU, PIERRE-JEAN 1983-10-27 WO disclosed