Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368046 | 0.96 | ESR1 (0.45) | ESR1ESR2BCHECNR2CNR1 | |
| SCHEMBL10367554 | 0.96 | ESR1 (0.45) | ESR1ESR2BCHECNR2CNR1 | |
| SCHEMBL10369154 | 0.95 | ESR1 (0.46) | ESR1ESR2BCHECNR2ACHE | |
| SCHEMBL10368940 | 0.85 | HRH3 (0.46) | BCHEACHEHRH3 | |
| SCHEMBL10370351 | 0.85 | WEE1 (0.46) | ESR1ESR2HTR7XDH | |
| SCHEMBL10369107 | 0.84 | CNR2 (0.43) | ESR1CNR2CNR1 | |
| SCHEMBL10370342 | 0.83 | ESR1 (0.39) | ESR1ESR2CNR2ACHEHRH3 | |
| SCHEMBL10368895 | 0.82 | CNR2 (0.36) | ESR1ESR2CNR2HRH3 | |
| SCHEMBL10832212 | 0.82 | HTR7 (0.50) | BCHECNR2CNR1HTR7HRH3 | |
| SCHEMBL10368866 | 0.81 | TMEM97 (0.44) | BCHEACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |