Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368209 | 0.86 | F10 (0.35) | CACNA2D1ATMALDH1A1F10 | |
| SCHEMBL10367627 | 0.85 | ESR1 (0.42) | ESR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10831303 | 0.83 | ATM (0.44) | CACNA2D1ATMPARP1HTR3AKDM4E | |
| SCHEMBL10369154 | 0.79 | ESR1 (0.46) | ESR1 | |
| SCHEMBL10367554 | 0.78 | ESR1 (0.45) | ESR1 | |
| SCHEMBL10368046 | 0.78 | ESR1 (0.45) | ESR1 | |
| SCHEMBL10370342 | 0.78 | ESR1 (0.39) | ESR1OPRM1 | |
| SCHEMBL10370351 | 0.77 | WEE1 (0.46) | ESR1KDM4EALDH1A1 | |
| SCHEMBL10368895 | 0.77 | CNR2 (0.36) | ESR1MTNR1B | |
| SCHEMBL10370283 | 0.75 | ESR1 (0.49) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |