Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470722 | 0.87 | GAA (0.56) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL10369782 | 0.84 | LCK (0.50) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL3009294 | 0.83 | LCK (0.49) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL11460779 | 0.81 | GAA (0.52) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL24453346 | 0.81 | APLNR (0.39) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL10370918 | 0.80 | GAA (0.54) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL10704773 | 0.79 | NPC1 (0.46) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL30542197 | 0.79 | NPC1 (0.46) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL11377779 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL11380228 | 0.79 | LRRK2 (0.40) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236646-B1 | ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-10 | — | — | EP | disclosed |
| US-4914117-A | ANTIDEPRESSANTS, CENTRAL NERVOUS SYSTEM ACTIVATORS; DOPAMINE ANTAGONISTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE-D-FRANCE (FR) | 1990-04-03 | — | — | US | disclosed |
| US-4835172-A | Novel benzamides, intermediates and process for the preparation and therapeutic use thereof | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1989-05-30 | — | — | US | disclosed |
| EP-0236646-A1 | Ortho-anisamides, process for their preparation and their pharmaceutical applications | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-09-16 | — | — | EP | disclosed |