Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.45 |
| ▸ | SELE | P16581 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10372239 | 0.85 | MPO (0.55) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL9375225 | 0.85 | ICAM1 (0.57) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL10373579 | 0.85 | MPO (0.54) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL6440669 | 0.85 | MPO (0.69) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL8767124 | 0.84 | MPO (0.68) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL9249134 | 0.82 | MPO (0.50) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL9371455 | 0.81 | MPO (0.57) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL12581251 | 0.80 | MPO (0.43) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL9246120 | 0.80 | MPO (0.52) | MPOCYSLTR1ICAM1SELESMN1; SMN2 | |
| SCHEMBL6568731 | 0.79 | MPO (0.59) | MPOCYSLTR1ICAM1SELESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187487-B1 | BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4703053-A | Benzothiophenes and benzofurans and antiallergic use thereof | WARNER-LAMBERT COMPANY (US) | 1987-10-27 | — | — | US | claimed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | claimed |