Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.43 |
| ▸ | KMT5A | Q9NQR1 | 4/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368034 | 0.95 | HRH3 (0.45) | ACHEHRH3 | |
| SCHEMBL10368865 | 0.95 | HRH3 (0.45) | ACHEHRH3 | |
| SCHEMBL10370014 | 0.94 | HRH3 (0.43) | HRH3KMT5AMAP2K7ESR1ESR2 | |
| SCHEMBL10370852 | 0.86 | HRH3 (0.54) | ACHEHRH3 | |
| SCHEMBL10371678 | 0.84 | CDC7 (0.51) | — | |
| SCHEMBL10831306 | 0.83 | HRH3 (0.54) | ACHEHRH3 | |
| SCHEMBL10371460 | 0.83 | GSK3B (0.40) | ACHEMAP2K7 | |
| SCHEMBL10367631 | 0.82 | GSK3B (0.41) | ACHEMAP2K7 | |
| SCHEMBL10368910 | 0.82 | CYP2D6 (0.45) | ACHE | |
| SCHEMBL10369412 | 0.81 | HRH3 (0.53) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |