Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368034 | 0.99 | HRH3 (0.45) | HRH3ACP1HTR7CDC7PGK1 | |
| SCHEMBL10368865 | 0.99 | HRH3 (0.45) | HRH3ACP1HTR7CDC7PGK1 | |
| SCHEMBL10371096 | 0.94 | ACHE (0.44) | HRH3MAP2K7KMT5AESR1ESR2 | |
| SCHEMBL10371678 | 0.90 | CDC7 (0.51) | ACP1CDC7WNT1DYRK1AKMT2A | |
| SCHEMBL10371460 | 0.89 | GSK3B (0.40) | HTR7CDC7DYRK1AMAP2K7CDK2 | |
| SCHEMBL10367631 | 0.88 | GSK3B (0.41) | HTR7CDC7DYRK1AMAP2K7CDK2 | |
| SCHEMBL10368910 | 0.88 | CYP2D6 (0.45) | DYRK1ACDK2 | |
| SCHEMBL10368569 | 0.85 | HRH3 (0.51) | HRH3 | |
| SCHEMBL10371164 | 0.84 | HRH3 (0.53) | HRH3ACP1 | |
| SCHEMBL10369412 | 0.84 | HRH3 (0.53) | HRH3ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |