Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.45 |
| ▸ | ACP1 | P24666 | 3/20 | 0.43 |
| ▸ | WNT1 | P04628 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368034 | 1.00 | HRH3 (0.45) | HRH3ACP1WNT1DYRK1AKMT2A | |
| SCHEMBL10370014 | 0.99 | HRH3 (0.43) | HRH3ACP1WNT1DYRK1AKMT2A | |
| SCHEMBL10371096 | 0.95 | ACHE (0.44) | HRH3ACHE | |
| SCHEMBL10371678 | 0.88 | CDC7 (0.51) | ACP1WNT1DYRK1AKMT2ACDC7 | |
| SCHEMBL10371460 | 0.87 | GSK3B (0.40) | DYRK1AHTR7CDC7ACHE | |
| SCHEMBL10367631 | 0.86 | GSK3B (0.41) | DYRK1AHTR7CDC7ACHE | |
| SCHEMBL10368910 | 0.86 | CYP2D6 (0.45) | DYRK1AKDM4EHSD17B10ACHE | |
| SCHEMBL10371164 | 0.86 | HRH3 (0.53) | HRH3ACP1KDM4EALDH1A1LMNA | |
| SCHEMBL10369412 | 0.86 | HRH3 (0.53) | HRH3ACP1KDM4EALDH1A1LMNA | |
| SCHEMBL10368569 | 0.84 | HRH3 (0.51) | HRH3KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |